Publications
Lourdes Infantes San Mateo


Structure-Based Modulation of the Ligand Sensitivity of a Tomato Dimeric Abscisic Acid Receptor Through a Glu to Asp Mutation in the Latch Loop
Lourdes Infantes, Maria Rivera-Moreno, Miguel Daniel-Mozo, Juan Luis Benavente, Javier Ocaña-Cuesta, Alberto Coego, Jorge Lozano-Juste, Pedro L. Rodriguez, and Armando Albert
Frontiers in Plant Science (2022) 13: 884029  (doi: 10.3389/fpls.2022.884029)


The structure and flexibility analysis of the Arabidopsis synaptotagmin 1 reveal the basis of its regulation at membrane contact sites
Juan L Benavente,  Dritan Siliqi,  Lourdes Infantes,  Laura Lagartera,  Alberto Mills,  Federico Gago,  Noemí Ruiz-López,  Miguel A Botella,  María J Sánchez-Barrena,  Armando Albert
Life Science Alliance (2021) published on line 18 August  (doi: 10.26508/lsa.202101152)

An Example of Polynomial Expansion: The Reaction of 3(5)-Methyl-1H-Pyrazole with Chloroform and Characterization of the Four Isomers.
Silva VLM, Silva AMS, Claramunt RM, Sanz D, Infantes L, Martínez-López Á, Reviriego F, Alkorta I, Elguero J
Molecules (2019) 24, E568  (doi: 10.3390/molecules24030568)

New Quinolyl Nitrones for Stroke Therapy: Antioxidant and Neuroprotective (Z)-N-t-Butyl-1-(2-chloro-6-methoxyquinolin-3-yl)methanimine Oxide as a New Lead-Compound for Ischemic Stroke Treatment
Chioua M., Martínez-Alonso E., Gonzalo-Gobernado R., Ayuso M.I., Escobar-Peso A., Infantes L., Hadjipavlou-Litina D., Montoya J.J., Montaner J., Alcázar A., Marco-Contelles J.
Journal of Medicinal Chemistry (2018) in press (doi: 10.1021/acs.jmedchem.8b01987)

The structure of four thallium tris(1H-pyrazol-1-yl)hydroborates in the solid state by X-ray crystallography and in solution by NMR and DFT-GIAO calculations
Infantes L., Moreno J.M., Claramunt R.M., Sanz D., Alkorta I., Elguero J.
Inorganica Chimica Acta (2018) 483, 402-410  (doi: 10.1016/j.ica.2018.08.009)

Deciphering the inhibition of the neuronal calcium sensor 1 and the guanine exchange factor Ric8a with a small phenothiazine molecule for the rational generation of therapeutic synapse function regulators
Roca C, Martínez-González L, Daniel-Mozo M, Sastre J, Infantes L, Mansilla A, Chaves-Sanjuán A, González-Rubio JM, Gil C, Cañada J,  Martínez A, Sánchez-Barrena MJ and Campillo NE
Journal of Medicinal Chemistry (2018) 61, 5910–5921  (doi:10.1021/acs.jmedchem.8b00088)

The structure of ligand-bound intermediates of crop ABA receptors highlights the role of the PP2C as necessary ABA co-receptor
Moreno-Alvero M, Yunta C, Gonzalez-Guzman M, Lozano-Juste J, Benavente JL, Arbona V, Menéndez M, Martínez-Ripoll M, Infantes L, Gomez-Cadenas A, Rodriguez PL, Albert A
Molecular Plant (2017) 10, 1250–1253 (doi:10.1016/j.molp.2017.07.004)

Interference of the complex between NCS-1 and Ric8a with phenothiazines regulates synaptic function and is an approach for fragile X syndrome
Alicia Mansilla, Antonio Chaves-Sanjuan, Nuria E. Campillo, Ourania Semelidou, Loreto Martínez-González, Lourdes Infantes, Juana María González-Rubio, Carmen Gil, Santiago Conde, Efthimio M. C. Skoulaki, Alberto Ferrús, Ana Martínez, María José Sánchez-Barrena
Proceedings of the National Academy of Sciences, PNAS (2017) 114, E999–E1008  (doi:10.1073/pnas.1611089114)

The structures of two scorpionates: Thallium tetrakis(3-phenyl-1H-pyrazol-1-yl)borate and potassium tetrakis(3-cyclopropyl-1H-pyrazol-1-yl)borate
Infantes, L.; Claramunt, R.M.; Sanz, D.; Alkorta, I.; Elguero, J.
Acta Crystallographica (2016) C72, 819-825 (doi:10.1107/S2053229616007385)

Prediction of H-bonding motifs for pyrazoles and oximes using the Cambridge structural database
Infantes, L.; Motherwell, S.
in Science of Crystal Structures: Highlights in Crystallography (2015) 269-280, Springer International Publishing (doi:10.1007/978-3-319-19827-9_28)

Synthesis of Enantiopure 3-Hydroxypiperidines from Sulfinyl Dienyl Amines by Diastereoselective Intramolecular Cyclization and [2,3]-Sigmatropic Rearrangement
Simal, C.; Bates, R.H.; Urena, M.; Giménez, I.; Koutsou, C.; Fernández De La Pradilla, R.; Viso, A.; Infantes, L.
Journal of Organic Chemistry (2015) 80, 7674-7692  (doi:10.1021/acs.joc.5b01307)

The Reaction of 2-Amino-4H-pyrans with N-Bromosuccinimide.
Samadi, A.; Silva, D.; Chioua, M.; Infantes, L.; Soriano, E.; Marco-Contelles, J.
Molecular Diversity (2015) 19, 103-122  (doi:10.1007/s11030-014-9560-4)


Experimental and Theoretical Studies on the Rearrangement of 2-Oxoazepane α,α-Amino Acids into 2’-Oxopiperidine β2,3,3-AminoAcids: An Example of Intramolecular Catalysis
Núñez-Villanueva, D.; Bonache, M. A.; Lozano, L.; Infantes, L.; Elguero, J.; Alkorta, I.; García-López, M.T.; González-Muñiz, R.; Martín-Martínez, M.
Chemistry - A European Journal (2015) 21, 2489-2500  (doi:10.1002/chem.201405640)


Silver Triflate-Catalyzed Cyclization of 2-Amino-6-propargyl-amineazines Leading to Iminoimidazoazines
Chioua, M.; Samadi, A.; Soriano, E.; Infantes, L.; Marco-Contelles, J.
Advanced Synthesis and Catalysis (2014) 356, 1235-1241  (doi:10.1002/adsc.201300799)


Sulfoxide-Directed Enantioselective Synthesis of Functionalized Tetrahydropyridines
Fernández de la Pradilla, R.; Simal, C.; Bates, R.H.; Viso, A.; Infantes, L.
Organic Letters (2013) 15, 4936-4939  (doi:10.1021/ol402141d)

Efficient Light Harvesters based on the 10-(1,3-Dithiol-2-ylidene)anthracene core
Bouit, P.A.; Infantes, L.; Calbo, J.; Viruela, R.; Ortí, E.; Delgado, J.L.; Martín, N.
Organic Letters (2013) 15, 4166-4169  (doi:10.1021/ol401841u)

The Structure and Dynamic Properties of 1H-Pyrazole-4-carboxylic acids in the Solid State
Infantes, L.; García, M.A.; López, C.; Claramunt, R.M.; Elguero, J.
Zeitschrift für Physikalische Chemie (2013) 227, 841-856  (doi:10.1524/zpch.2013.0377)


Highly functionalized β,γ–diamino compounds through reductive amination of amino acid-derived β–keto esters
P. Pérez-Faginas, M.T. Aranda, M.T. García-López, L. Infantes, A. Fernández-Carvajal, J.M. González-Ros, A. Ferrer-Montiel and R. González-Muñiz
PLoS ONE (2013) 8, e53231   (doi:10.1371/journal.pone.0053231)


The Silver-catalyzed Cyclization of N-(prop-2-yn-1-yl)pyridin-2-amines
M. Chioua, E. Soriano, L. Infantes, M.L. Jimeno, J. Marco-Contelles and A. Samadi
European Journal of Organic Chemistry (2013) 1, 35-39   (doi:10.1002/ejoc.201201258)

Azepane quaternary amino acids as effective inducers of 310 helix conformations
D. Nuñez-Villanueva, L. Infantes, M.T. Garcia-Lopez, R. Gonzalez-Muñiz, M. Martín-Martínez
Journal of Organic Chemistry (2012) 77, 9833-9839   (doi:10.1021/jo301379r)


The Structural Domains of Pseudomonas aeruginosa Phosphorylcholine Phosphatase Cooperate in Substrate Hydrolysis: 3D Structure and Enzymatic Mechanism
Lourdes Infantes, Lisandro Horacio Otero, Paola Rita Beassoni, Cristhian Boetsch, Angela Teresita Lisa, Carlos Eduardo Domenech and Armando Albert
Journal of Molecular Biology (2012) 423, 503–514  (doi:10.1016/j.jmb.2012.07.024)

A Practical Two-Step Synthesis of Imidazo[1,2-a]pyridines from N-(prop-2-yn-1-yl)pyridin-2-amines

D. Sucunza, A. Samadi, M. Chioua, D.B. Silva, C. Yunta, L. Infantes, M.C. Carreiras, E. Soriano, J. Marco-Contelles
Chemical Communications (2011) 47, 5043-5045  (doi:10.1039/C1CC10641D)

Quaternary α,α,-2-Oxoazepane alpha-Amino Acids: Synthesis from Ornithine-Derived β-Lactams and Incorporation into Model Dipeptides
D. Nuñez-Villanueva, M.A. Bonache, L. Infantes, M.T. Garcia-Lopez, M. Martin-Martinez, R. Gonzalez-Muniz
Journal of Organic Chemistry (2011) 76, 6592-6603  (doi:10.1021/jo200894d)


Controlling Optical Properties and Function of BODIPY by Using Asymmetric Substitution Effects
J. Bañuelos-Prieto, A.R. Agarrabeitia, I. García-Moreno, I. López Arbeloa, A. Costela, L. Infantes, M.E. Perez-Ojeda, M. Palacios-Cuesta and M.J. Ortiz
Chemistry European Journal (2010) 16, 14094-14105   (doi:10.1002/chem.201002095)

Botelho da Silva, D., Samadi, A., Infantes, L., Carreiras, M.C. and Marco-Contelles, J.
Synthesis of (E)-diethyl 6,60-(diazene-1,2-diyl)bis(5-cyano-2-methyl-4-phenylnicotinates), a new type of 2,20-azopyridine dyesodification of pancreatic lipase properties by directed molecular evolution
Tetrahedron Letters (2010) 51, 6278-6281 (doi:10.1016/j.tetlet.2010.09.095)

Colin, D.Y., Deprez-Beauclair, P., Silva, N., Infantes, L. and Kerfelec, B.
Modification of pancreatic lipase properties by directed molecular evolution
Protein Engineering Design & Selection (2010) 23, 365-373
(doi:10.1093/protein/gzq008)

Further Evidence for 2-Alkyl-2-carboxyazetidines as γ-Turn Inducers
J.L. Baeza, G. Gerona-Navarro, K. Thompson, M.J. Prez de Vega, L. Infantes, M.T. García-Lopez, R. Gonzalez-Muñiz and M. Martin-Martinez
Journal of Organic Chemistry (2009) 74, 8203-8211

The molecular structure of 1,3-dimethyl-4-phenyl-1H-pyrazole-5-carboxylic acid

C.Fernández-Fernández, N.Jagerovic, I.Alkorta, C.M.Maya, L.Infantes and J.Elguero
Arkivoc (2008) 74-84

Structural changes in the BODIPY dye PM567 enhancing the laser action in liquid and solid media

I.García-Moreno, F.Amat-Guerri, M.Liras, A.Costela, L.Infantes, R.Sastre, F.López Arbeloa, J.Bañuelos Prieto and Í.López Arbeloa

Adv. Funct. Mater., (2007) 17, 3088-3098

Synthesis, Photophysical Properties and Laser Behavior of 3-Amino and 3-Acetamido BODIPY Dyes
M.Liras, J.Bañuelos Prieto, M.Pintado-Sierra, F.López Arbeloa, I.García-Moreno, Á.Costela, L.Infantes, R.Sastre, and F.Amat-Guerri
Org. Lett., (2007) 9, 4183-4186

Organic crystal hydrates: what are the important factors for formation
L.Infantes, L.Fábián and W.D.S.Motherwell
Crys. Eng. Comm., (2007) 9, 65-71

Knowledge-Based Approaches to Crystal Design
W.D.S.Motherwell, J.Chisholm, E.Pidcock, J. van de Streek, L.Infantes, and F.H.Allen
Crys. Eng. Comm., (2006) 8, 11-28

Substituent Effects on Enthalpies of Formation of Nitrogen Heterocycles: 2-Substituted Benzimidazoles and Related Compounds
L.Infantes, O.Mó, M.Yáñez, M.V.Roux, P.Jiménez, J.Z.Dávalos, M.Temprado, M.A.V.Ribeiro da Silva, M.D.M.C.Ribeiro da Silva, L.M.P.F.Amaral, P.Cabildo, R.Claramunt and J.Elguero
J. Phys. Chem. A, (2006) 110, 2535-2544

Classification of hydrogen-bond motives in crystals of NH-pyrazoles: a mixed empirical and theoretical approach
I.Alkorta, J.Elguero*, C.Foces-Foces and L.Infantes
Arkivoc (2006) Part(ii), 15-30

Water Oligomers in Crystal Hydrates- What’s News and What Isn’t?
M.Mascal*, L.Infantes* and J.Chisholm
Angewandte Chemie, Int. Ed., (2006) 45, 32-36

The unusual transformation of an aromatic 1H-imidazole into a non-aromatic 2H-imidazole
A. de la Hoz, A.Sánchez-Migallón, M. del C.Mateo, P.Prieto, L.Infantes and J.Elguero
Struct. Chem., (2005) 16(5), 485-490

Hydrogen bond competition between chemical groups: new methodology and the Cambridge Structural Database
L.Infantes and W.D.S.Motherwell
Z. Kristallogr., (2005) 220, 333-339

Neural network prediction of secondary structure in crystals: hydrogen bonds systems in pyrazole derivatives
J.Fayos, L.Infantes and F.H.Cano
Cryst. Growth Des., (2005) 5(1), 191-200

The probable number of hydrogen-bonded contacts for chemical groups in organic crystal structures
L.Infantes and W.D.S.Motherwell
Chem. Comm., (2004) 1166-1167

Prediction of H-Bonding Motifs for Pyrazoles and Oximes Using the Cambridge Structural Database
L.Infantes and W.D.S.Motherwell
Struct. Chem., (2004) 15(3), 173-184

Extended motifs from water clusters in organic molecular crystals
L.Infantes , J.Chisholm and W.D.S.Motherwell
Crys. Eng. Comm. (2003) 5(85), 480-486

The structure of a 4-nitroso-5-aminopyrazole and its salts: tautomerism, protonation and E/Z isomerism
M.H.Holschbach, D.Sanz, R.M.Claramunt, L.Infantes, S.Motherwell, P.R.Raithby, M.L.Jimeno, D.Herrero, I.Alkorta, N.Jagerovic and J.Elguero
J. Org. Chem. (2003) 68(23), 8831-8837

The Structure of Tris(3’,5’-Dimethylpyrazol-1-yl)-s-Triazine and its Use as a Ligand in Coordination Chemistry
A.Guerrero, F.A.Jalón, B.R.Manzano, R.M.Claramunt, P.Cabildo, L.Infantes, F.H.Cano and J.Elguero
Chem. Heterocycl. Comp. (2003) 39, 1396-1403

1,2,4,5-Tetrazines vs. Carboxylic Acid Dimers. Molecular Chemistry vs. Supramolecular Chemistry
L.Infantes, M.F.Mahon, L.Male, P.R.Raithby, S.J.Teat, J.Sauer, N.Jagerovic, J.Elguero, and S.Motherwell
Helv. Chim. Acta (2003) 86, 1205-1221

The structure of N-hydroxylophine-N-oxide in the solid state
A.Sánchez-Migallón, A.de la Hoz, M.A.García, C.López, R.M.Claramunt, L.Infantes, S.Motherwell, K.Shankland, H.Nowell, I.Alkorta, and J.Elguero
Helv. Chim. Acta (2003) 86, 1026-1039

Water Clusters in organic molecular crystals
L.Infantes and W.D.S.Motherwell
Crys. Eng. Comm. (2002) 4, 454-461

The annular tautomerism of 4(5)-phenylimidazole
R.M.Claramunt, M.D.Santa-María, L.Infantes, F.H.Cano and J.Elguero
J. Chem. Soc., Perkin Trans. 2 (2002) 564-568

2,4,6-Tris(azol-1-yl)-1,3,5-triazines: a new class of multidentate ligands
V.Milata, R.M.Claramunt, P.Cabildo, M.D.Santa-María, P.Cornago, L.Infantes, F.H.Cano and J.Elguero
Heterocycles (2001) 55, 905-924

Aminopyrazoles and Their Conjugated Acids: An X-Ray Study of 3,5-Dimethyl-4-Aminopyrazole and the Picrate of 3(5)-Aminopyrazole
L.Infantes, C.Foces-Foces, R.M.Claramunt, C.López and J.Elguero
J. Heterocyclic Chem. (1999) 36, 595-600

3(5),4-Dimethyl- and 3,4,5-Trimethylpyrazole at 200K. X-ray crystallography and quantum-chemical analysis
L.Infantes, C.Foces-Foces and J.Elguero
Acta Cryst. (1999) B55, 441-447

Packing modes in eight 3-ethoxycarbonylpyrazole derivatives. Influence of the substituents on the crystal structure and annular tautomerism
L.Infantes, C.Foces-Foces, R.M.Claramunt, C.López, N.Jagerovic and J.Elguero
Heterocycles (1999) 50, 227-242

Tautomerism of NH-pyrazolinones in the solid state: the case of 3(5)-ethoxycarbonyl-5(3)-hydroxypyrazole
L.Infantes, C.Foces-Foces, R.M.Claramunt, C.López and J.Elguero
J. Mol. Struct. (1998) 447, 71-79

The structure of aminoazoles and its relationship with aromaticity. Crystal and molecular structure of two polymorphic forms of 4-aminopyrazole
L.Infantes, C.Foces-Foces, P.Cabildo, R.M.Claramunt, O.Mó, M.Yáñez and J.Elguero
Heterocycles (1998) 49, 157-168

Solid-state structure of NH-pyrazolium hydrochlorides and hydrobromides by X-ray crystallography and 13C CPMAS NMR
C.Foces-Foces, L.Infantes, R.M.Claramunt, C.López, N.Jagerovic and J.Elguero
J. Mol. Struct. (1997) 415, 81-92

Structure and Tautomerism of 3(5)-Amino-5(3)-arylpyrazoles in the Solid State and in Solution: an X-Ray and NMR Study
J.Quiroga, B.Insuasty, C.Foces-Foces, L.Infantes, R.M.Claramunt*, P.Cabildo, J.A.Jiménez and J.Elguero
Tetrahedron (1997) 53, 10783-10802

Host-Guest Chemistry. The Structure and Proton Disorder of the Three-Component Crystal Formed by 3(5)-methyl-4-nitropyrazole, (R,R)-(-)-trans-4,5-bis(hydroxydiphenylmethyl)-2,2-dimethyl-1,3-dioxolane and Toluene
F.Toda, K.Tanaka, C.Foces-Foces, L.Infantes, R.M.Claramunt, C.Lopez and J.Elguero
J. Phys. Org. Chem. (1996) 9, 611-618

Mixed crystals f pyrazoles and benzoic acids. Part 1. The molecular structure of 3,5-dimethylpyrazole-2,4,6-trimethylbenzoic acid co-crystals
C.Foces-Foces, L.Infantes, F.Aguilar-Parrilla, N.S.Golubev, H.H.Limbach and J.Elguero
J. Chem. Soc.,  Perkin Trans. 2 (1996) 349-353

Gas Phase (Ion Cyclotron Resonance Spectrometric) and Solid State (Crystallographic) Studies of Highly Substituted Pyrazoles
J.L.M.Abboud, C.Foces-Foces, M.Herreros, H.Homan, L.Infantes, R.Notario, A.W.Krebs, J.Neubauer, J.Elguero and N.Jagerovic
J. Phys. Org. Chem. (1996) 9, 79-86

New Synthetic Approaches to Condensed Pyridazinones: Alkylpyridazinyl Carbonitriles as Building Blocks for the Synthesis of Condensed Pyridazinones
H.Al-Awadhi, F.Al-Omran, M.H.Elnagdi, L.Infantes, C.Foces-Foces, N.Jagerovic and J.Elguero
Tetrahedron (1995) 51, 12745-12762

Optical Resolution of 1,3-Dimethyl-5-phenyl-2-pyrazoline by Diastereoisomeric Complex Formation with an Optically Active Host Compound: X-Ray and Molecular Structure of the Complex
F.Toda, K.Tanaka, L.Infantes, C.Foces-Foces, R.M.Claramunt and J.Elguero
J. Chem. Soc., Chem. Commun. (1995) 1453-1454