Publications
2024
ABA-receptor agonist iSB09 decreases soil water consumption and increases tomato CO2 assimilation and water use efficiency under drought stress
Mayra Sanchez-Olvera, Constanza Martin-Vasquez, Cristian Mayordomo,
Jonatan Illescas-Miranda, Mar Bono, Alberto Coego, Jana Alonso,
Mercedes Hernández-González, David Jiménez-Arias,
Javier Forment, Armando Albert, Antonio Granell, Andrés A.
Borges, Pedro L. Rodriguez
Environmental and Experimental Botany (2024) 225, 105847 (doi: 10.1016/j.envexpbot.2024.105847)
Inverse regulation of SOS1 and HKT1 protein localization and stability by SOS3/CBL4 in Arabidopsis thaliana
Francisco
Gámez-Arjona, Hee Jin Park, Elena García, Rashid Aman, Irene
Villalta, Natalia Raddatz, Raul Carranco, Akhtar Ali, Zahir Ali, Shah
Zareen, Anna De Luca, Eduardo O. Leidi, Miguel Daniel-Mozo, Zheng-Yi
Xu, Armando Albert, Woe-Yeon Kim, Jose M Pardo, Clara
Sánchez-Rodriguez, Dae-Jin Yun, Francisco J. Quintero
Proceedings of the National Academy of Sciences (2024) 121(9) e2320657121 (doi: 10.1073/pnas.2320657121)
2023
Continuous
development in macromolecular
crystallography with CCP4
Martín Martinez-Ripoll and Armando Albert
Acta Crystallographica, Section D
(2023) D79, 447-448 (doi:
10.1107/S205979832300445X) (see also this link)
Structure-guided engineering of a receptor-agonist pair for inducible activation of the ABA adaptive response to drought
Jorge Lozano-Juste, Lourdes Infantes, Irene Garcia-Maquilon, Rafael
Ruiz-Partida, Ebe Merilo, Juan Luis Benavente, Adrian Velazquez-Campoy,
Alberto Coego, Mar Bono, Javier Forment, Begoña Pampín,
Paolo Destito, Adrián Monteiro, Ramón Rodríguez,
Jacobo Cruces, Pedro L. Rodriguez, and Armando Albert
Science Advances (2023) 9(10) (doi: 10.1126/sciadv.ade9948) (see also a video)
2022
El "Rockefeller" cumple 90 años en la vanguardia de la investigación científica
Albert, A., Martínez-Ripoll, M.
Anales de Química (2022) 118(4), 273-274 (link to the article)
Structure-Based Modulation of the Ligand Sensitivity of a Tomato
Dimeric Abscisic Acid Receptor Through a Glu to Asp Mutation in the
Latch Loop
Lourdes Infantes, Maria Rivera-Moreno, Miguel Daniel-Mozo, Juan Luis
Benavente, Javier Ocaña-Cuesta, Alberto Coego, Jorge
Lozano-Juste, Pedro L. Rodriguez, and Armando Albert
Frontiers in Plant Science (2022) 13: 884029 (doi: 10.3389/fpls.2022.884029)
PYL1- and PYL8-like ABA Receptors of Nicotiana benthamiana Play a Key Role in ABA Response in Seed and Vegetative Tissue
Gaston
A. Pizzio, Cristian Mayordomo, Jorge Lozano-Juste, Victor
Garcia-Carpintero, Marta Vazquez-Vilar, Sergio G. Nebauer, Kacper P.
Kaminski, Nikolai V. Ivanov, Juan C. Estevez, Maria Rivera-Moreno,
Armando Albert, Diego Orzaez and Pedro L. Rodriguez
Cells (2022) 11, 795 (doi: 10.3390/cells11050795)
2021
It
takes two to tango: Unraveling a new post-translational modification
involved in SnRK2.6 activation
Miguel Daniel-Mozo, Armando Albert
Molecular Plant
(2021) 14, 1–3 (doi:
10.1016/j.molp.2021.08.003)
The structure and flexibility analysis of
the Arabidopsis synaptotagmin
1 reveal the basis of its regulation at membrane contact sites
Juan
L Benavente, Dritan Siliqi, Lourdes
Infantes, Laura Lagartera,
Alberto Mills, Federico Gago, Noemí
Ruiz-López, Miguel A Botella,
María J Sánchez-Barrena, Armando Albert
Life
Science Alliance (2021) published on line 18 August
(doi:
10.26508/lsa.202101152)
Synaptotagmins
at the endoplasmic reticulum-plasma membrane contact sites maintain
diacylglycerol homeostasis during abiotic stress
Ruiz-Lopez N,
Pérez-Sancho J, Esteban Del Valle A, Haslam RP, Vanneste S,
Catalá R,
Perea-Resa C, Van Damme D, García-Hernández S,
Albert A, Vallarino J,
Lin J, Friml J, Macho AP, Salinas J, Rosado A, Napier JA, Amorim-Silva
V, Botella MA.
Plant Cell (2021) 33,
2431–2453 (doi:
10.1093/plcell/koab122)
Pharmacological Approaches for the Modulation of the Potassium Channel
KV4.x and KChIPs
Cercós P, Peraza DA, Benito-Bueno A, Socuéllamos
PG,
Aziz-Nignan A, Arrechaga-Estévez D, Beato E,
Peña-Acevedo
E, Albert A, González-Vera JA, Rodríguez Y,
Martín-Martínez M, Valenzuela C,
Gutiérrez-Rodríguez M.
International Journal of
Molecular Sciences (2021) 22, 1419 (doi:
10.3390/ijms22031419)
Identification of ABA Receptor Agonists Using a Multiplexed
High-Throughput Chemical Screening
Jorge Lozano-Juste, Irene García-Maquilón,
José
Brea, Rocío Piña, Armando Albert, Pedro L.
Rodriguez,
María Isabel Loza
in Plant
Chemical Genomics. Methods in Molecular Biology (2021) vol. 2213,
Hicks G.R., Zhang C. (eds). Humana, New York, NY (doi:
10.1007/978-1-0716-0954-5_9)
2020
Recognition
and activation of the plant AKT1 potassium channel by the kinase CIPK23
Maria
Jose Sanchez-Barrena, Antonio Chaves-Sanjuan, Natalia Raddatz, Imelda
Mendoza, Alvaro Cortes, Federico Gago, Juana Maria Gonzalez-Rubio, Juan
Luis Benavente, Francisco J. Quintero, Jose M. Pardo, Armando Albert
Plant
Physiology (2020) 182, 2143–2153 (doi:10.1104/pp.19.01084)
2019
PYR/PYL/RCAR ABA receptors
Pedro L. Rodriguez, Jorge Lozano-Juste, Armando Albert
Advances
in Botanical Research (2019) 92, 51-82 (doi:10.1016/bs.abr.2019.05.003)
2018
Structural
Biology of Salt and Drought Tolerance in Plants
Sánchez-Barrena, María J; Martinez-Ripoll,
Martín; and Albert, Armando
In eLS
(2018). John
Wiley & Sons, Ltd: Chichester (doi:
10.1002/9780470015902.a0027628)
2017
The structure of ligand-bound
intermediates of crop ABA receptors highlights the role of the PP2C as
necessary ABA co-receptor
Moreno-Alvero
M, Yunta C, Gonzalez-Guzman M, Lozano-Juste J, Benavente JL, Arbona
V, Menéndez M, Martinez-Ripoll M, Infantes L, Gomez-Cadenas
A,
Rodriguez PL, Albert A
Molecular
Plant (2017) 10, 1250–1253 (doi:10.1016/j.molp.2017.07.004)
2016
Calcium-dependent
oligomerization of CAR proteins at cell membrane modulates ABA signaling
Maira Diaza, Maria Jose Sanchez-Barrena, Juana Maria Gonzalez-Rubio,
Lesia Rodriguez, Daniel Fernandez, Regina Antoni, Cristina Yunta, Borja
Belda-Palazon, Miguel Gonzalez-Guzman, Marta Peirats-Llobet, Margarita
Menendez, Jasminka Boskovic, Jose A. Marquez, Pedro L. Rodriguez, and
Armando Albert
Proceedings
of the National Academy of Sciences, PNAS (2016) 113,
E396-E405 (doi:
10.1073/pnas.1512779113)
2015
The bacteriocin AS-48 requires dimer dissociation followed by
hydrophobic interactions with the membrane for antibacterial activity.
Cebrián R, Martínez-Bueno M, Valdivia E, Albert
A, Maqueda M, Sánchez-Barrena MJ.
Journal
of Structural Biology (2015) 190, 162–172
(doi:10.1016/j.jsb.2015.03.006)
Molecular recognition of PTS-1 cargo proteins by Pex5p: implications
for protein mistargeting in primary hyperoxaluria
Mesa-Torres N, Tomic N, Albert A, Salido E, Pey AL.
Biomolecules
(2015) 5, 121-141 (doi:10.3390/biom5010121)
2014
C2-Domain
Abscisic Acid-Related Proteins Mediate the Interaction of PYR/PYL/RCAR
Abscisic Acid Receptors with the Plasma Membrane and Regulate Abscisic
Acid Sensitivity in Arabidopsis
Lesia
Rodriguez, Miguel Gonzalez-Guzman, Maira Diaz, Americo Rodrigues, Ana
C. Izquierdo-Garcia, Marta Peirats-Llobet, Maria A. Fernandez, Regina
Antoni, Daniel Fernandez, Jose A. Marquez, Jose M. Mulet, Armando
Albert, and Pedro L. Rodriguez
The
Plant Cell (2014) 26, 4802-4820 (doi:10.1105/tpc.114.129973)
Structural
basis of the regulatory mechanism of the plant CIPK family of protein
kinases controlling ion homeostasis and abiotic stress
Antonio
Chaves-Sanjuan, Maria Jose Sanchez-Barrena, Juana Maria Gonzalez-Rubio,
Maria Moreno, Paula Ragel, Marta Jimenez, Jose M. Pardo, Martin
Martinez-Ripoll, Francisco J. Quintero, and Armando Albert
Proceedings
of the National Academy of Sciences, PNAS (2014) 111, 4532-4541
(doi:10.1073/pnas.1407610111)
The
consensus-based approach for gene/enzyme replacement therapies and
crystallization strategies: the case of human alanine:glyoxylate
aminotransferase
Mesa-Torres N, Yunta C, Fabelo-Rosa I, Gonzalez-Rubio JM, Sanchez-Ruiz
JM, Salido E, Albert A, Pey AL
Biochemical
Journal (2014) 462, 453-463 (doi:10.1042/BJ20140250)
Tomato
PYR/PYL/RCAR abscisic acid receptors show high expression in root,
differential sensitivity to the abscisic acid agonist quinabactin, and
the capability to enhance plant drought resistance
Gonzalez-Guzman
M, Rodriguez L, Lorenzo-Orts L, Pons C, Sarrion-Perdigones A, Fernandez
MA, Peirats-Llobet M, Forment J, Moreno-Alvero M, Cutler SR, Albert A,
Granell A, Rodriguez PL
Journal
of Experimental Botany (2014) 65, 4451-4464
(doi:10.1093/jxb/eru219)
Preliminary crystallographic
analysis of the ankyrin-repeat domain of Arabidopsis thaliana
AKT1: identification of the domain boundaries for protein
crystallization
Chaves-Sanjuán A, Sánchez-Barrena MJ,
González-Rubio JM, Albert A.
Acta
Crystallographica (2014) F70, 509-512 (doi:10.1107/S2053230X14005093)
A
través del cristal. Cómo la
cristalografía ha cambiado la visión del mundo
Martín
Martínez-Ripoll, Juan A. Hermoso y Armando Albert (coord.)
Editorial
CSIC-Catarata (2014) ISBN:
978-84-00-09800-1.
Comunicación celular
a escala atómica
Armando Albert
in A
través del cristal. Cómo la
cristalografía ha cambiado la visión del mundo
(2014). (M.
Martínez-Ripoll, J.A. Hermoso y Armando Albert, coord.), CSIC-Catarata, pp. 171-182, ISBN:
978-84-00-09800-1.
A través del cristal y más allá
Martín
Martínez-Ripoll, Juan A. Hermoso y Armando Albert
in A
través del cristal. Cómo la
cristalografía ha cambiado la visión del mundo
(2014). (M.
Martínez-Ripoll, J.A. Hermoso y Armando Albert, coord.), CSIC-Catarata, pp.
183-188, ISBN:
978-84-00-09800-1.
A single mutation in the GSTe2 gene allows tracking of metabolically
based insecticide resistance in a major malaria vector
Riveron JM, Yunta C, Ibrahim SS, Djouaka R, Irving H, Menze BD, Ismail
HM, Hemingway J, H. Ranson, A. Albert and C.S. Wondji
Genome Biology (2014) 15, R27
(doi:10.1186/gb-2014-15-2-r27)
2013
The
role of protein denaturation energetics and molecular chaperones in the
aggregation and mistargeting of mutants causing primary hyperoxaluria
type I
Mesa-Torres, N., Fabelo-Rosa, I., Riverol, D., Yunta, C., Albert, A.,
Salido, E., Pey, A.L.
PLoS
ONE (2013) 8, e71963 (doi:10.1371/journal.pone.0071963)
The PYL4 A194T mutant uncovers a key role of
PYR1-LIKE4/PROTEIN PHOSPHATASE 2CA interaction for abscisic acid
signaling and plant drought resistance
Pizzio, G.A., Rodriguez, L., Antoni, R., González-Guzman,
M.,
Yunta, C., Merilo, E., Kollist, H., Albert, A., Rodriguez, P.L.
Plant
Physiology (2013) 163, 441-55 (doi:
10.1104/pp.113.224162)
Protein homeostasis defects of alanine-glyoxylate aminotransferase: new
therapeutic strategies in primary hyperoxaluria type I
Pey, A.L., Albert, A., Salido, E.
Biomed
Research International (2013) 2013:687658 (doi:10.1155/2013/687658)
Structural Biology
of a Major Signaling Network that Regulates Plant Abiotic Stress: The
CBL-CIPK Mediated Pathway
María
José Sánchez-Barrena, Martín
Martínez-Ripoll and Armando Albert
International
Journal of Molecular Sciences (2013) 14, 5734-5749
(doi:10.3390/ijms14035734)
2012
Structural
insights on the plant Salt-Overly-Sensitive 1 (SOS1) Na+/H+
antiporter
Rafael
Núñez-Ramírez, María
José Sánchez-Barrena, Irene Villalta, Juan F.
Vega, Jose M. Pardo, Francisco J. Quintero, Javier Martinez-Salazar and
Armando Albert
Journal
of Molecular Biology (2012) 424, 283-294 (doi:10.1016/j.jmb.2012.09.015)
The
Structural Domains of Pseudomonas
aeruginosa Phosphorylcholine Phosphatase Cooperate in
Substrate
Hydrolysis: 3D Structure and Enzymatic Mechanism
Lourdes Infantes,
Lisandro Horacio Otero, Paola Rita Beassoni, Cristhian Boetsch, Angela
Teresita Lisa, Carlos Eduardo Domenech and Armando Albert
Journal of
Molecular Biology (2012) 423, 503–514 (doi:10.1016/j.jmb.2012.07.024)
An analysis of subdomain orientation, conformational change and
disorder in relation to crystal packing of aspartic proteinases
D. Bailey, E.P. Carpenter, A. Coker, S. Coker, J. Read, A.T. Jones, P.
Erskine, C.F. Aguilar, M. Badasso, L. Toldo, F. Rippmann, J.
Sanz-Aparicio, A. Albert, T.L. Blundell, N.B., Roberts, S.P. Wood and
J.B. Cooper
Acta
Crystallographica (2012) D68, 541-552 (doi:
10.1107/S0907444912004817)
2011
The structure of Arabidopsis Thaliana
OST1 provides insights into the kinase regulation mechanism in response
to osmotic stress
Cristina Yunta, Martín Martínez-Ripoll, Jian-Kang
Zhu and Armando Albert
Journal of
Molecular Biology (2011) 414, 135–144 (doi:10.1016/j.jmb.2011.09.041)
Crystallization and preliminary crystallographic analysis of a C2
protein from Arabidopsis thaliana
Maira Diaz, Lesia Rodriguez, Miguel Gonzalez-Guzman, Martin
Martinez-Ripoll and Armando Albert
Acta
Crystallographica (2011) F67, 1575–1578
(doi:10.1107/S1744309111040541)
SnRK2.6/OST1
from Arabidopsis
thaliana:
cloning, expression, purification, crystallization and preliminary
X-ray analysis of K50N and D160A mutants
Cristina Yunta, Martin
Martinez-Ripoll and Armando Albert
Acta
Crystallographica (2011) F67, 364–368 (doi:10.1107/S1744309110053807)
2010
Crystallization and
preliminary X-ray diffraction analysis of Pseudomonas aeruginosa
phosphorylcholine phosphatase
L.H. Otero, P.R.
Beassoni, C.E. Domenech, A.T. Lisa and A. Albert
Acta
Crystallographica (2010) F66, 957-960 (doi:10.1107/S1744309110024061)
Structure
of GroEL in Complex with an Early Folding Intermediate of Alanine
Glyoxylate Aminotransferase
Armando Albert, Cristina Yunta, Rocío Arranz,
Álvaro
Peña, Eduardo Salido, José María
Valpuesta and
Jaime Martín-Benito
Journal
of Biological Chemistry (2010) 285, 6371-6376 (doi:10.1074/jbc.M109.062471)
2008
Crystallization and preliminary
crystallographic analysis of merohedrally twinned crystals of MJ0729, a
CBS-domain protein from Methanococcus
jannaschii
P.
Fernández-Millán, D. Kortazar, M. Lucas, M. L.
Martínez-Chantar, E.
Astigarraga, J. A. Fernández, O. Sabas, A. Albert, J. M.
Mato and L. A.
Martínez-Cruz
Acta Crystallographica (2008) F64, 605-609
2007
The structure of the
C-terminal domain of the protein kinase AtSOS2 bound to the calcium
sensor
AtSOS3
María
José Sánchez-Barrena, Hiroaki Fujii, Ivan Angulo,
Martín Martínez-Ripoll, Jian-Kang
Zhu and Armando Albert
Molecular
Cell
(2007) 26, 427-435 [PDF-copy]
The
complex between SOS3 and SOS2 regulatory domain from Arabidopsis
thaliana: cloning, expression, purification,
crystallization and
preliminary X-ray analysis
Sánchez-Barrena, M.J.,
Moreno-Pérez,, S., Angulo, I., Martínez-Ripoll,
M. and Albert, A.
Acta Crystallographica (2007) F63, 568-570
2006
Cell signaling and function
organized by PB1 domain interactions
Moscat, J., Diaz-Meco, M.T.,
Albert, A. and Campuzano, S.
Molecular Cell (2006) 23, 631-640
[PDF-copy]
La Química de la vida
a escala atómica
Hermoso, J.A., Sanz Aparicio, J.
and Albert A.
Anales de Química (2006)
102(4), 15-22 [PDF-copy]
Biología a escala
atómica
Albert, A.
La
razón (2006) 2869, 29
2005
Structure of the functional
domain of phi 29 replication organizer
Asensio,
JL, Albert, A, Muñoz-Espín, D,
González, C,
Hermoso, JA, Villar, L, Jiménez-Barbero, J, Salas, M and
Meijer,
W
Journal of Biological Chemistry (2005)
280, 20730-20739
Structural basis for membrane
anchorage of viral phi 29 DNA during replication
Albert A, Munoz-Espin D, Jimenez
M, Asensio JL, Hermoso JA, Salas M, Meijer WJ.
Journal of Biological Chemistry (2005)
280, 42486-42489
The structure of the Arabidopsis
thaliana SOS3: molecular mechanism of
sensing calcium for salt stress response
Sánchez-Barrena, M.J.,
Martínez-Ripoll, M., Zhu,
J.K. and Albert, A.
Journal of
Molecular Biology (2005) 345, 1253-1264
2004
SOS3
(salt overlay sensitive 3) from Arabidopsis
thaliana: expression,
purification, crystallization and preliminary X-ray analysis
Sánchez-Barrena, M.J.,
Martínez-Ripoll, M., Zhu, J.K. and Albert, A.
Acta Crystallographica (2004) D60,
1272-1274
Structure of concanavalin A at pH
8: bound solvent and crystal contacts
Lopez-Jaramillo FJ,
Gonzalez-Ramirez LA, Albert A, Santoyo-Gonzalez F, Vargas-Berenguel A,
Otalora F
Acta Crystallographica (2004) D60,
1048-1046
Peptide AS-48: prototype of a new
class of cyclic bacteriocins
Maqueda M, Galvez A, Bueno MM,
Sanchez-Barrena MJ, Gonzalez C, Albert A, Rico M, Valdivia E.
Current Protein and Peptide Science
(2004) 5, 399-416
Functional characterization of
the yeast Ppz1 phosphatase inhibitory subunit Hal3: a mutagenesis study
Muñoz, I, Ruiz, A,
Marquina, M, Barcelo, A, Albert, A, Ariño, J.
Journal of Biological Chemistry (2004)
279, 42619-42627
2003
Structure of bacteriocin AS-48:
from soluble state to membrane bound state
Sanchez-Barrena, M.J.,
Martinez-Ripoll, M., Galvez, A., Valdivia, E., Maqueda, M., Cruz, V.
and Albert A.
Journal of Molecular Biology (2003) 334,
541-549
Structural basis for selective
recognition of pneumococcal cell wall by modular endolysin from phage
Cp-1
Hermoso,
J.A., Monterroso, B., Albert, A., Galan, B., Ahrazem, O., Garcia, P.,
Martinez-Ripoll, M., Garcia, J.L. and Menendez, M.
Structure (2003) 11, 1239-1249
2002
Crystallization
and preliminary X-ray diffraction studies of the complete modular
endolysin from Cp-1, a phage infecting Streptococcus pneumoniae
Monterroso, B., Albert, A.,
Martinez-Ripoll, M., Garcia, P., Garcia, J.L., Menéndez, M.,
Hermoso, J.A.
Acta Crystallographica (2002) D58,
1487-1489
TrwD, the hexameric traffic
ATPase encoded by plasmid R388, induces membrane destabilization and
hemifusion of lipid vesicles
Machon, C., Rivas, S., Albert,
A., Goñi, F.M., de la Cruz, F.
Journal of Bacteriology (2002) 184,
1661-1668
Structural Enzymology of Li+
sensitive / Mg2+ dependent Phosphatases
Patel, S., Martinez-Ripoll, M.,
Blundell, T.L. and Albert, A.
Journal of Molecular Biology
(2002) 320, 1087-1094
2000
Structure
of yeast Hal2p, a major target of lithium and sodium toxicity.
Identification of a framework of interactions determining cation
sensitivity
Albert, A., Yenush, L.,
Gil-Mascarell, R., Rodriguez, P.L., Patel, J., Martinez-Ripoll, M.,
Blundell, T.L. and Serrano, R.
Journal of Molecular Biology (2000) 295,
927-938
The X-ray
structure of the FMN binding protein atHal3 provides the structural
basis for the activity of a regulatory domain involved in signal
transduction
Albert, A., Martínez
Ripoll, M., Espinosa-Ruiz, A., Rodriguez, P.L.,
Culiañez-Macia, F. and Serrano, R.
Structure
(2000) 8, 961-969
1999
Molecular study of the rat liver
NADH: Cytochrome C oxidoreductase complex during development and aging
Torres-Mendoza, C.E., Albert A.
and de la Cruz, M.J.
Molecular and Cellular Biochemistry
(1999) 195, 133-142
A six-stranded double-psi beta
barrel is shared by several protein superfamilies
Castillo, R.M., Mizuguchi, K.,
Dhanaraj, V., Albert, A., Blundell, T.L. and Murzin, A.G.
Structure (1999) 7, 227-236
Making the most of commercial
sparse-matrix protein crystallization screening kits
Albert, A. and Martinez-Ripoll,
M.
Journal of Applied Crystallography (1999)
32, 336-338
1998
Crystal structure of aspartate
decarboxylase at 2.2 Å resolution provides evidence for an
ester in
protein self-processing
Albert, A., Dhanaraj, V., Genschel, U., Khan, G., Ramjee, M.K., Pulido,
R., Sibanda, B.L., von Delft, F., Witty, M., Blundell, T.L., Smith,
A.G. and Abell, C.
Nature
Structural
and Molecular Biology (1998) 5, 289-293 (doi:10.1038/nsb0498-289)
Protein
Engineering Aspartic Proteinases: Site-Directed Mutagenesis,
Biochemical Characterisation, and X-Ray Analysis of Chymosins with
Substituted Single Amino Acid Substitutions and Loop Replacements
Albert,
A., Blundell, T.L., Dhanaraj, V., Donate, L.E., Groves, M., Guruprasad,
K., Nugent, P.G., Orprayoon, P., Pitts, J.E., Rufino, S., Srinivasan,
N.,Williams, M. and Wilsher, J.
Adv. in Experimental Medicine and Biology
(1998) 436, 169-177
The Aspartic Proteinases: An
Historical Overview
Blundell, T.L., Guruprasad, K.,
Albert, A., Williams, M., Sibanda, B.L. and Dhanaraj, V.
Adv. in Experimental Medicine and Biology
(1998) 436, 1-13
1997
Aspartic proteinases: From the
first X-ray photos of pepsin crystals to hundreds of 3-D structures
Blundell, T.L., Guruprasad, K.,
Albert, A., Williams, M., Sibanda, B.L. and Dhanaraj, V.
Current Science (1997) 72, 483-489
Diethyl
2-Benzimidazol-1-ylsuccinate-Picric Acid (1/1). An Inclusion Molecular
Complex
Zadarenko, P., Gil, M.S., Lopez,
P., Ballesteros, P., Fonseca, I. and Albert, A.
Acta Crystallographica (1997) B53, 961-967
Tetrafluoro
and dichloro derivatives of thiophene-fused DCNQI- and TCNQ-type
acceptors: A synthetic, electrochemical and crystallographic study
Martin, N., deMiguel, P., Seoane,
C., Albert, A. and Cano, F.H.
Journal of Materials Chemistry (1997) 7,
25-29
A study
on the scope of the photochemical ring contraction of substituted
2-amino-3-cyano-4H-pyrans to cyclobutenes: crystal structure of
3-carbamoyl-3-cyano-1-ethoxycarbonyl-4-isopropyl-2-phenylcyclobutene
Armesto, D., Albert, A., Cano,
F.H., Martin, N., Ramos, A., Rodriguez, M., Segura, J.L. and Seoane, C.
J. Chemical Society-Perkin Transactions I
(1997) 22, 3401-3405
1996
New Synthetic Route to
1,2,4-Thiadiazolines and 1,3-Thiazolines via Thiadiazolopyridinium Salts
Martinez, A., Castro, A.,
Fonseca, I., Martinez-Ripoll, M., Cano, F.H. and Albert, A.
Heterocycles (1996) 43, 2657-2666
First asymmetric synthesis of
3-alkoxycarbonyl-2-amino-4-aryl-4H-naphtho[1,2-b]pyrans
Martin, N., MartinezGrau, A.,
Seoane, C., Marco, J.L., Albert, A. and Cano, F.H.
Journal of Heterocyclic Chemistry (1996)
33, 27-31
Protein
engineering loops in aspartic proteinases: site-directed mutagenesis,
biochemical characterization and X-ray analysis of chymosin with a
replaced loop from rhizopuspepsin
Nugent, P.G., Albert, A.,
Orprayoon, P., Pitts, J.E., Blundell, T.L. and Dhanaraj, V.
Protein Engineering (1996) 9, 885-893
Synthesis,
characterization, and theoretical study of sulfur-containing
donor-acceptor DCNQI derivatives with photoinduced intramolecular
electron transfer
Martin,
N., Segura, J.L., Seoane, C., Orti, E., Viruela, P.M., Viruela, R.,
Albert, A., Cano, F.H., VidalGancedo, J., Rovira, C. and Veciana, J.
Journal of Organic Chemistry (1996) 61,
3041-3054
Synthesis and X-ray structure of
1,4-bis[4-(N,N-dimethylamino)- phenyl]buta-1,3-diyne: charge-transfer
complex with acceptors
Rodriguez, J.G., Ramos, S.,
Martin-Villamil, R., Fonseca, I. and Albert, A.
J. Chemical Society, Perkin Transactions
I (1996) 6, 541-543
1995
Interacciones
aromáticas en empaquetamientos cristalinos
Albert, A. and Cano, F.H.
in Cristalografía,
Serie:
Nuevas
Tendencias (1995). CSIC, Cano,
F.H.,
Foces-Foces, C. y Martínez-Ripoll, M. (eds.)
Asymmetric Synthesis of
4-Alkyl-3,5-dialkoxycarbonyl-2,6-dimethyl-1,4-dihydropyridines
Martin, N., Martinez-Grau, A.,
Seoane, C., Marco, J.L., Albert, A. and Cano, F.H.
Tetrahedron: Asymmetry (1995) 6, 877-880
Tricyanovinylthiophenes as Novel
Electron Acceptors for Organic Metals
de Lucas, A.I., Martin, N., de
Miguel, P., Seoane, C., Albert, A. and Cano, F.H.
Journal of Materials Chemistry (1995) 5,
1141-1145
1994
Asymmetric Synthesis of
3-Alkoxycarbonyl-2-amino-5-cyano-4,6- diphenyl-4H-pyrans
Martin, N., Martinez-Grau, A.,
Seoane, C., Marco, J.L., Albert, A. and Cano, F.H.
Tetrahedron: Asymmetry (1994) 5, 1435-1438
Development of Methods for the
Synthesis of Chiral, Highly Functionalized 2-Amino-4-Aryl-4H-Pyrans
Marco, J.L., Martin, N.,
Martinez-Grau, A., Seoane, C., Albert, A. and Cano, F.H.
Tetrahedron (1994) 50, 3509-3528
Single-Component Donor-Acceptor
Organic Semiconductors Derived from TCNQ
Bando, P., Martin, N., Segura,
J.L., Seoane, C., Orti, E., Viruela, P.M., Viruela, R., Albert, A. and
Cano, F.H.
Journal of Organic Chemistry (1994) 59,
4618-4629
1993
Michael Addition of Malonitrile to alpha-Acetylcinnamamides
Martin, N., Martinez-Grau, A.,
Seoane, C., Marco, J.L., Albert, A. and Cano, F.H.
Liebigs Annalen der Chemie (1993) 801-804
A Novel Molecule for the Design
of Organic Conductors: 2,5-bis
(3-phenylpropyl)-7,7,8,8-Tetracyano-p-Quinodimethane
Martin, N., Segura, J.L., Seoane,
C., Albert, A. and Cano, F.H.
Synthetic Metals (1993), 55-57, 1730-1734
7,7-Diphenylnorbornane: The first
Cofacial Diphenylmethane Derivative
Garcia Martinez, A., Osio
Barcina, J., Albert, A., Cano, F.H. and Subramanian, L.R.
Tetrahedron Letters (1993) 34, 6753-6756
Reactivity
of Cinnamonitriles with 2-Cyano- and 2-Ethoxycarbonyl-acetohydrazides:
A Novel One-step Preparation and Crystal Structure of
3-Oxopyrazolo[3,4-b]pyridines
Hadi, A., Martin, N., Mendez, C.,
Quintero, M., Seoane, C., Soto, J.L., Albert, A. and Cano, F.H.
J. Chemical Society, Perkin Transactions
I (1993) 1743-1748
Michael Addition of Malonitrile
to Chiral alpha-Acylacrylates
Marco, J.L., Martin, G., Martin,
N., Martinez-Grau, A., Seoane, C., Albert, A., Cano, F.H.
Tetrahedron (1993) 49, 7133-7144
Novel
Molecules for the Design of Organic Conductors. Synthesis of
7,7,8,8-Tetracyano-2,5-bis(3-phenylpropyl)-p-quinodimethane and
N,N'-Dicyano-2,5-bis(3,-phenylpropyl)-p-quinodiimine and X-Ray
Structure of the TCNQ Derivative
Martin, N., Segura, J.L., Seoane,
C., Albert, A. and Cano, F.H.
J. Chemical Society, Perkin Transactions
I (1993) 2363-2368
1992
Syntheses,
electrochemical properties and crystal structure of
tetracyano-p-quinodimethane (TCNQ) derivatives with pi-extended systems
containing a sulfur atom
de la Cruz, P., Martin, N.,
Miguel, F., Seoane, C., Albert, A., Cano, F.H., Leverenz, A. and
Hanack, M.
Synthetic Metals (1992) 48, 59-64
Synthesis
and Crystal Structure of Piperidinium 2-Aryl [1,2,4]
triazolo[1,5-a]pyridinides and their Neutralization to 2-Aryl
[1,2,4]triazolo[1,5-a]pyridines
Hadi, A., Martin, N., Seoane, C.,
Soto, J.L., Albert, A. and Cano, F.H.
Journal of Heterocyclic Chemistry (1992) 29, 1229-1235
The First Asymmetric Synthesis of
Polyfunctionalized 4H-Pyrans via Michael Addition of Malonitrile to
2-Acyl Acrylates
Gonzalez, R., Martin, N., Seoane,
C., Marco, J.L., Albert, A. and Cano, F.H.
Tetrahedron Letters (1992) 33, 3809-3812
Novel pi-Extended Thiophene-Fused
Electron Acceptors for Organic Metals
Cruz, P., Martin, N., Miguel, F.,
Seoane, C., Albert, A., Cano, F.H., Gonzalez, A. and Pingarron, J.M.
Journal of Organic Chemistry (1992) 57,
6192-6198
Synthesis, and Structural,
Conformational and Pharmacological Studies of new Fentanyl Derivatives
of the Norgranatane System
Fernandez,
M.J., Huertas, R.M., Galvez, E., Orjales, A., Berisa, A., Labeaga, L.,
Gago, F., Fonseca, I., Sanz-Aparicio, J., Cano, F.H., Albert, A. and
Fayos, J.
J. Chemical Society, Perkin Transactions
II (1992) 687-695
Synthesis,
Electrochemistry, and Crystal Structure of N,N'-dicyanoquinonediimine
(DCNQI) Derivatives Containing Fused Benzene Rings
Martin, N., Navarro, J.A.,
Seoane, C., Albert, A. and Cano, F.H.
Journal of Organic Chemistry (1992) 57,
5726-5730
A Novel Bridgehead Azocine. The
end of a controversy
Martin, N., Quinteiro, M.,
Seoane, C., Albert, A., Cano, F.H. and Abramovitch, R.A.
Tetrahedron
(1992) 48, 1581-1584